Selected Publications

  • Zhang S, Sanders AR, Duan J. Modeling PTSD neuronal stress responses in a dish. Nat Neurosci. 2022

    • Loss of function of OTUD7A in the schizophrenia-associated 15q13.3 deletion impairs synapse development and function in human neurons. Kozlova A, Zhang S, Kotlar AV, Jamison B, Zhang H, Shi S, Forrest MP, McDaid J, Cutler DJ, Epstein MP, Zwick ME, Pang ZP, Sanders AR, Warren ST, Gejman PV, Mulle JG, Duan J. Am J Hum Genet. 2022

    • Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Nature. 2022

      • Genomic evidence consistent with antagonistic pleiotropy may help explain the evolutionary maintenance of same-sex sexual behavior in humans. Zietsch BP, Sidari MJ, Abdellaoui A, Maier R, Långström N, Guo S, Beecham GW, Martin ER, Sanders AR, Verweij KJH. Nat Hum Behav. 2021

        • Genome-Wide Linkage and Association Study of Childhood Gender Nonconformity in Males. Sanders AR, Beecham GW, Guo S, Dawood K, Rieger G, Krishnappa RS, Kolundzija AB, Bailey JM, Martin ER. Arch Sex Behav. 2021

          • Allele-specific open chromatin in human iPSC neurons elucidates functional disease variants.  Zhang S, Zhang H, Zhou Y, Qiao M, Zhao S, Kozlova A, Shi J, Sanders AR, Wang G, Luo K, Sengupta S, West S, Qian S, Streit M, Avramopoulos D, Cowan CA, Chen M, Pang ZP, Gejman PV, He X, Duan J. Science. 2020

            • The “All of Us” Research Program. All of Us Research Program Investigators; Denny JC, Rutter JL, Goldstein DB, Philippakis A, Smoller JW, Jenkins G, Dishman E. N Engl J Med. 2019

              • Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior. Ganna A, Verweij KJH, Nivard MG, Maier R, Wedow R, Busch AS, Abdellaoui A, Guo S, Sathirapongsasuti JF; 23andMe Research Team, Lichtenstein P, Lundström S, Långström N, Auton A, Harris KM, Beecham GW, Martin ER, Sanders AR, Perry JRB, Neale BM, Zietsch BP. Science. 2019

                • Deconvolution of Transcriptional Networks Identifies TCF4 as a Master Regulator in Schizophrenia. Torshizi AD, Armoskus C, Zhang S, Zhang H, Souaiaia T, Forrest MP, Evgrafov OV, Knowles JA, Duan J, Wang K. Science Adv, 2019

                • Genome-Wide Association Study of Male Sexual Orientation. Sanders AR, Beecham GW, Guo S, Dawood K, Rieger G, Badner JA, Gershon ES, Krishnappa RS, Kolundzija AB, Duan J; MGS Collaboration, Gejman PV, Bailey JM, Martin ER. Sci Rep. 2017

                • Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis. Sanders AR, Drigalenko EI, Duan J, Moy W, Freda J, Göring HHH, Gejman PV. Transl Psychiatry. 2017

                • Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Forrest MP, Zhang H, Moy W, McGowan H, Leites C, Dionisio LE, Xu Z, Shi J, Sanders AR, Greenleaf WJ, Cowan CA, Pang ZP, Gejman PV, Penzes P, Duan J. Cell Stem Cell. 2017

                • Genome-wide scan demonstrates significant linkage for male sexual orientation. Sanders AR, Martin ER, Beecham GW, Guo S, Dawood K, Rieger G, Badner JA, Gershon ES, Krishnappa RS, Kolundzija AB, Duan J, Gejman PV, Bailey JM. Psychol Med. 2015

                • Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants. Duan J, Sanders AR, Moy W, Drigalenko EI, Brown EC, Freda J, Leites C, Göring HH; MGS, Gejman PV. Hum Mol Genet. 2015

                • MicroRNA-9 and microRNA-326 regulate human dopamine D2 receptor expression and the microRNA-mediated expression regulation is altered by a genetic variant. Shi S, Leites C, He D, Schwartz D, Moy M, Shi J, Duan J. J Biol Chem. 2014

                • Biological insights from 108 schizophrenia-associated genetic loci. Schizophrenia Working Group of the Psychiatric Genomics Consortium. Nature. 2014

                • Transcriptome study of differential expression in schizophrenia. Sanders AR, Göring HH, Duan J, Drigalenko EI, Moy W, Freda J, He D, Shi J; MGS, Gejman PV. Hum Mol Genet. 2013

                • Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J… 185 other authors …, O’Donovan MC, Daly MJ, Gejman PV. Genome-wide association study identifies five new schizophrenia loci. Nat Genet. 2011

                • Copy Number Variants in Schizophrenia: Confirmation of Five Previous Findings and New Evidence for 3q29 Microdeletions and VIPR2 Duplications. Levinson DF, Duan J, Oh S, Wang K, Sanders AR, Shi J, 9 others, Kendler KS, Freedman R, Dudbridge F, Pe’er I, Hakonarson H, Bergen SE, Fanous AH, Holmans PA, Gejman PV. Am J Psychiatry. 2011

                • The Internet-based MGS2 control sample: self-report of mental illness. Sanders AR, Levinson DF, Duan J, Dennis JM, Li R, Kendler KS, Rice JP, Shi J, Mowry BJ, Amin F, Silverman JM, Buccola NG, Byerley WF, Black DW, Freedman R, Cloninger CR, Gejman PV. Am J Psychiatry. 2019

                • The role of genetics in the etiology of schizophrenia. Gejman PV, Sanders AR, Duan J. Psychiatr Clin North Am. 2010

                • Common variants on chromosome 6p22.1 are associated with schizophrenia. Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe’er I, Dudbridge F, Holmans PA, Whittemore AS, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, Crowe RR, Oksenberg JR, Mirel DB, Kendler KS, Freedman R, Gejman PV. Nature. 2009

                • No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, Burrell GJ, Rice JP, Nertney DA, Olincy A, Rozic P, Vinogradov S, Buccola NG, Mowry BJ, Freedman R, Amin F, Black DW, Silverman JM, Byerley WF, Crowe RR, Cloninger CR, Martinez M, Gejman PV. Am J Psychiatry. 2008

                • Genome wide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. Suarez BK, Duan J, Sanders AR, Hinrichs AL, Jin CH, Hou C, Buccola NG, Hale N, Weilbaecher AN, Nertney DA, Olincy A, Green S, Schaffer AW, Smith CJ, Hannah DE, Rice JP, Cox NJ, Martinez M, Mowry BJ, Amin F, Silverman JM, Black DW, Byerley WF, Crowe RR, Freedman R, Cloninger CR, Levinson DF, Gejman PV. Am J Hum Genet. 2006

                • Synonymous mutations in the human dopamine receptor D2 (DRD2) affect mRNA stability and synthesis of the receptor. Duan J, Wainwright MS, Comeron JM, Saitou N, Sanders AR, Gelernter J, Gejman PV. Hum Mol Genet. 2003

                For a complete list of publications, please visit the bibliographies of Dr. Alan Sanders and Dr. Jubao Duan.